Duragesic Patch Time Onset

Fetynal patches are synthetic narcotic analgesic with a rapid onset and short duration of action. In the mid-1990s, fentanyl was first introduced for widespread.

1 Fentanyl patches Durogesic for chronic pain FENT-a-nil Summary Oral morphine is preferred when an opioid is required for severe chronic pain, because of its.

This Privacy Policy applies to the websites www.medscape.com and www.medscape.org, which are operated by WebMD LLC WebMD and Medscape LLC Medscape, respectively, including the mobile optimized versions of these websites collectively, the Sites. Except where otherwise noted, statements in this Privacy Policy with respect to the Sites also apply to the Medscape Device Applications or Apps for iPhone, iPad and Android devices which include Medscape Mobile, Medscape Medpulse and Medscape Business of Medicine. The Sites and Apps are referred to as the Medscape Network. References to we, us or our refer to WebMD and Medscape.

This Privacy Policy describes how we may collect, use and disclose information about users of the Services. The Services for purposes of this Privacy Policy means the Sites, the Apps and all information and services provided to you in connection with your use of the Sites and Apps including, without limitation, news, reference content, tools, applications, sponsored programs, advertising, email communications, continuing medical education and discussion boards. We may share information collected under this Privacy Policy among the respective Sites and Apps that we each own or control, but information collected under this Privacy Policy is always protected under the terms of this Privacy Policy.

In this section of our Privacy Policy, we discuss the information we may collect about you in connection with your use the Services, which can include Personal Information i.e., information that we can use to identify you, such as your name or email address and Non-Personal Information i.e., information that we do not use to identify you. As described below, we may associate Non-Personal Information with Personal Information and upon doing so such information will become Personal Information.

Registration. When you register to become a member of the Medscape Network, we request certain Personal Information from you such as your name and e-mail address, zip code, profession, occupation and specialty. You may choose to update and/or supplement the Personal Information that you provided at registration at any time through your account settings.

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Market Research: From time to time, we may invite you to participate in market research surveys for WebMD and market research surveys conducted on behalf of third party sponsors either by WebMD or a third party Sponsored Surveys, where in this context sponsor means the provider of products and services who commissioned the survey. WebMD surveys may be administered by one of our companies or by a third party acting on our behalf. For some surveys, you may be asked to provide contact information for honoraria fulfillment.

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Cookies and Web Beacons. We collect Non-Personal Information about your use of the Sites and the Apps, as further described in the Mobile Device Application section, below, through the use of cookies and web beacons. Cookies are small data files that we assign to your computer s hard drive when you visit a Site, an App, or open an email. Web beacons are graphic image files imbedded in a web page typically used to monitor activity on a web page and send back to its home server which can belong to the host site, a network advertiser or some other third party information from your browser, such as the IP address, the URL of the page on which the beacon is located and the content viewed, the type of browser that is accessing the site and the ID number of any cookies on your computer previously placed by that server. Most browser software can be set to reject all cookies, however, if you choose to reject cookies then you will not be able to access the Sites or your use of the Sites may be limited.

We use web beacons and cookies to: i track usage of the Services; ii help us deliver more relevant advertising and content to users of the Services; iii assess which Services our users access; and iv track who has opened our emails. If you are a member of the Medscape Network, we may elect to associate our cookies and the information collected by our cookies with your registration information, thereby making the cookie information Personal Information.

Third parties under contract with WebMD may use cookies or web beacons to help WebMD deliver advertising to you on properties within the Medscape Network and on properties outside of the Medscape Network that are not owned and operated by WebMD. Advertisers that market to you through the Services may use their own cookies, web beacons or other online tracking technologies in the banner advertisements served to you. Some advertisers use companies other than WebMD to serve these ads on their behalf and to monitor users responses to ads, and these companies Ad Servers may also collect Non-Personal Information through the use of cookies or web beacons. We do not control these third parties use of cookies or web beacons or how they manage the Non-Personal Information they gather through them. However, our Advertising Policy prohibits advertisers and their Ad Servers from collecting Personal Information from our users based on their use of the Services. Our Advertising Policy also prohibits advertisers from linking any Non-Personal Information that they collect from our users use of the Services to Personal Information about our users that they or others collect in other ways or from other sources.

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Emails You Send to Us. This Privacy Policy does not apply to information, content, business information, ideas, concepts or inventions that you send to us by email or other non-Site communication. If you want to keep content or business information, ideas, concepts or inventions private or proprietary, do not send them to us in an email or other non-Site communication such as regular mail.

Information from Third Party Sources. We may also collect additional information about members of the Medscape Network from third party sources to assist us in providing the Services. For example, we may use third party information to verify and update your registration information and to personalize the Services provided to you, including advertising.

How We May Use Your Information

In this section of our Privacy Policy, we discuss how we may use the Personal Information and Non-Personal Information that we collect about you.

Communications. By registering for the Services, you are consenting to receive certain communications. Specifically, we may use your registration information to send you communications about our products and services and the products and services of our third party sponsors through pop-ups, banners and e-mails. You may also subscribe to receive certain e-mail newsletters sent to registered users from time to time which you may manage through the newsletter subscriptions area within your account settings.

Marketing and Advertising. In connect with advertising and marketing activities, WebMD may:

Target advertising and marketing communications based on information that we collect about your use of the Services and information about you that we obtain from third party sources. For example, a user that WebMD believes is a cardiologist may be served cardiology-related advertisements on both WebMD-owned and third party websites that a user that WebMD believes is a neurologist will not see. Similarly, a user that WebMD believes is a healthcare professional that treats diabetes may be served advertisements for new diabetes therapies that other users would not see. WebMD serves these ads through the use of cookies and web beacons, as described above. WebMD may also geographically target advertising and marketing communications based on your Internet Protocol IP address.

Personalize the Services, including the content and advertising that registered users see within the Medscape Network, on third party sites and through other communications such as e-mail, based on their interests. For example, you may see different articles and advertisements in different places on www.medscape.com and in e-mails that we send to you based on i information you have shared with WebMD such as your specialty; ii information that WebMD has obtained by observing your previous activity within the Medscape Network; or iii information that WebMD has received from third party sources, as described in this Privacy Policy.

Work with third parties to allow advertisers to serve you ads within the Medscape Network using information that such advertisers have collected from third party sources. For example, if you looked at an advertisement for an automobile on a third party website you may receive an advertisement for that automobile on a Site through the use of cookies.

Member Profiles. As described above, we use web beacons and cookies to track your use of the Services, including content consumption, and may associate this information with other information that we have about you, including Personal Information, thereby creating a profile of you that we may update from time to time Member Profile.

Research, Development and Evaluation Activities. We use information that we collect about users of our Services, including Personal Information, to evaluate and improve the effectiveness of the Services including advertising and Sponsored Programs, to develop new Services and for market analysis. We may combine this information with information that we obtain from third parties.

Account Management. We may use your account information to administer your account, respond to your inquiries you send to us and to send you administrative communications about the Services.

Disclosure of Your Information to Third Parties

Companies and People Who Work for Us: We each contract with other companies and individuals to help us provide the Services and to otherwise assist us in the operation of our businesses. For example, we may host one of our Sites on another company s computers, hire technical consultants to maintain our clinical tools, work with companies to analyze data, provide marketing assistance including assisting us in targeting our advertisements as described herein or to provide customer service or fulfillment services. In addition, if you are a healthcare professional, we may request that a third party validate your licensure status and other information against available databases of healthcare professionals. Notwithstanding anything to the contrary herein, we may provide these companies and individuals with Personal Information about users of our Services so that they can fulfill their responsibilities to us, however, we do require that they agree to limit their use of this Personal Information to the fulfillment of these responsibilities.

Aggregated Information. We may provide aggregated information about users of our Services to third parties as we deem appropriate in our sole discretion. For example, WebMD may tell a customer what percentage of registered users of the Medscape Network reside in a particular geographical area or specialize in a particular clinical area, or what percentage of participants in a market research survey selected a particular response to a survey question. We may also use Personal Information to evaluate the performance of an advertising campaign and may provide aggregate outcomes information to the advertiser.

Advertising and Sponsored Programs: We may provide your Personal Information to third party sponsors of advertisements and Sponsored Programs. Specifically, when you are exposed to an advertisement through the Services, whether on a Site, in a newsletter or through some other means, or when you engage in a Sponsored Program, e.g., access a sponsored information resource or open a Sponsored Program e-mail from WebMD Professional, WebMD may provide your Personal Information, such as your name and specialty, but not your contact information such as email address and postal address, to the sponsor of the advertisement or Sponsored Program and/or its agents on the sponsor s behalf. We may also provide such third parties with details about your engagement with the advertisement or Sponsored Program e.g., whether you viewed or otherwise interacted with certain content, your answers to any polling questions contained in the Sponsored Program that you have chosen to provide and information about you that we have received from third parties. Additionally, when you register as a member of the Medscape Network, we may provide your Personal Information, excluding contact information, to potential sponsors of advertisements and Sponsored Programs that may be offered or provided to you through the Services. We are not responsible for how these third parties use your information and manage your privacy.

Member Profiles. WebMD may provide Member Profiles excluding contact information, such as email address and postal address, and information about your participation in specific named CME and CE activities to third parties, including our pharmaceutical manufacturer customers, which they may use for their business purposes including marketing. We require these third parties to agree that they will use Member Profiles in accordance with applicable laws and regulations. By registering as a member of the Medscape Network and using the Services, you consent to WebMD s disclosure of your Member Profiles to third parties as described herein.

Market Research Surveys: If you receive remuneration for participating in a Sponsored Survey, we may be required to provide the sponsor or the market research company acting on its behalf with your Personal Information for the sponsor s recordkeeping and/or regulatory reporting purposes. If you chose to access a Sponsored Survey that is conducted by a third party market research company, we may identify you to this company through the survey link. Sometimes market research companies send us lists of individuals they wish to reach with particular Sponsored Surveys, and we may inform these companies which of these individuals are members of the Medscape Network so that they can manage their survey recruitment needs accordingly. Also, certain market research survey opportunities made available to you through the Services require the market research company to contact you directly to conduct the Sponsored Survey. We will inform you in the associated survey invitation that we intend to provide your contact information to the market research company that is conducting the Sponsored Survey so that you can decide at such time if you wish to proceed with the opportunity. We do not disclose your Sponsored Survey responses to the associated sponsor in a manner identifiable to you.

Continuing Medical Education: We may share your Personal Information with the accreditors of our continuing education programs. Medscape is accredited by the Accreditation Council for Continuing Medical Education ACCME, the American Nurses Credentialing Center and the Accreditation Council for Pharmacy Education to provide continuing education to physicians, nurses and pharmacists, respectively collectively, CME/CE. As an accredited entity, Medscape is required to periodically submit Personal Information about CME/CE participants and the CME/ CE activities that Medscape certifies, as requested by the applicable accrediting entity. Medscape and WebMD Global LLC WebMD Global, an affiliated company that also provides continuing medical education activities through the Medscape Network, may provide your Personal Information to other accredited providers who certify CME/CE offered through the Services as required by these other providers to process the credits that that you earn by completing the applicable CME/CE activity, to fulfill their reporting obligations to the ACCME and other accrediting bodies and as required for their internal recordkeeping purposes. Supporters of Medscape and WebMD Global s continuing medical education activities will receive only aggregated data about CME/CE activities that they support including participation and outcomes measurement.

Logging in to Another Website Using Your Medscape Credentials: Certain third party websites permit you to log in using your Medscape username and password. If you choose to log in to one of these websites using your Medscape log in credentials, we may give this website information included in your registration profile including Personal Information such as your name, specialty, occupation and email address, but not your Medscape username and password, which the operator of the website has agreed to use in accordance with its website s privacy policy. You should review the third party website s privacy policy before logging in. If the privacy policy of the third party site permits, we may receive information about your use of this third party site, which we may use in accordance with this Privacy Policy.

Consent: We may disclose your Personal Information to a third party in a manner not addressed by this Privacy Policy subject to your consent.

Business Transfers: If one of us transfers a business unit such as a subsidiary or an asset such as a website to another company, that company will be required to treat any Personal Information collected under this Privacy Policy consistent with the applicable terms of this Privacy Policy.

Legal Requirements: We may release account and other Personal Information when we believe release 1 is required to comply with valid legal requirements such as a law, regulation, search warrant, subpoena or court order; or 2 is reasonable in response to a physical threat to you or others, to protect property or defend or assert legal rights of us or others.

We have implemented technology and security policies and other measures to protect the personal data that we have under our control from unauthorized access, improper use, alteration, unlawful or accidental destruction, and accidental loss. We also require that all of our employees and others who have access to or are associated with the processing of your data respect your confidentiality.

We use security methods to determine the identity of registered users, so that appropriate rights and restrictions can be enforced for that user. Reliable verification of user identity is called authentication. We use both passwords and usernames to authenticate users. Users are responsible for maintaining the security of their Medscape login credentials.

Access to Information and Choices

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Note to Users Outside of the United States

WebMD, Medscape and WebMD Global are located in the United States. We will collect, store, and process your information that we obtain from the use of the Services in the United States and these activities shall be governed by applicable United States laws and regulations and this Privacy Policy. The information may be available to the United States government or its agencies under legal process made in the United States. In addition, we may transfer your information outside the United States to service providers and customers with operations in other countries. By using the Services, you consent to such collection, storage and processing in the United States and elsewhere, though the United States and other jurisdictions may not afford the same level of data protection as considered adequate in your own country. We will take reasonable steps to protect your information.

The Medscape Network and the Services are designed and intended for use by adults, and are not intended for nor designed to be used by children under the age of 18. We do not collect Personal Information from any person we know is under the age of 18.

We reserve the right to modify this Privacy Policy at any time and any changes will be effective upon posting of the modified Policy unless we advise otherwise. If we make any material changes to this Policy we will notify you by email sent to the email address included in your account profile and/or by means of a notice on the Medscape Network at the time that the change becoming effective. We encourage you to periodically review this Privacy Policy for the latest information on our privacy practices. If you do not accept the terms of this Privacy Policy, we ask that you do not register with us and that you do not use the Services. By continuing to use the Services after changes are made to this Privacy Policy, you are consenting to such changes.

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Effective date: November 24, 2015.

Medscape Access

DURAGESIC fentanyl transdermal system CII contains a high concentration of a potent Schedule II opioid agonist, fentanyl. Schedule II opioid substances which include fentanyl, hydromorphone, methadone, morphine, oxycodone, and oxymorphone have the highest potential for abuse and associated risk of fatal overdose due to respiratory depression. Fentanyl can be abused and is subject to criminal diversion. The high content of fentanyl in the patches DURAGESIC may be a particular target for abuse and diversion.

DURAGESIC is indicated for management of persistent, moderate to severe chronic pain that:

Requires continuous, around-the-clock opioid administration for an extended period of time, and

Cannot be managed by other means such as nonsteroidal analgesics, opioid combination products, or immediate-release opioids

should ONLY be used in patients who are already receiving opioid

therapy, who have demonstrated opioid tolerance, and who require a

total daily dose at least equivalent to DURAGESIC 25

mcg/hr. Patients who are considered opioid-tolerant are those who have

been taking, for a week or longer, at least 60 mg of morphine daily, or

at least 30 mg of oral oxycodone daily, or at least 8 mg of oral

hydromorphone daily or an equianalgesic dose of another opioid.

Because serious or life-threatening hypoventilation could occur, DURAGESIC is contraindicated:

In patients who are not opioid-tolerant

In the management of acute pain or in patients who require opioid analgesia for a short period of time

In the management of post-operative pain, including use after out-patient or day surgeries e.g., tonsillectomies

In the management of mild pain

In the management of intermittent pain e.g., use on an as needed basis prn

See CONTRAINDICATIONS section of the full Prescribing Information for further information.

Since the peak fentanyl concentrations generally occur between 20 and

72 hours of treatment, prescribers should be aware that serious or

life-threatening hypoventilation may occur, even in opioid-tolerant

patients, during the initial application period.

DURAGESIC with all cytochrome P450 3A4 inhibitors

such as ritonavir, ketoconazole, itraconazole, troleandomycin, clarithromycin, nelfinavir, nefazodone, amiodarone, amprenavir, aprepitant, diltiazem, erythromycin, fluconazole, fosamprenavir, grapefruit juice, and verapamil may result in an increase in fentanyl

plasma concentrations, which could increase or prolong adverse drug

effects and may cause potentially fatal respiratory depression.

Patients receiving DURAGESIC and any CYP3A4 inhibitors

should be carefully monitored for an extended period of time and dosage

adjustments should be made if warranted. See CLINICAL

PHARMACOLOGY-Drug Interactions, WARNINGS, PRECAUTIONS, and DOSAGE AND

ADMINISTRATION sections of the full Prescribing Information for further

The safety of DURAGESIC has not been established in children under 2 years of age. DURAGESIC should be administered to children only if they are opioid-tolerant and 2 years of age or older. See PRECAUTIONS - Pediatric Use section of the full Prescribing Information.

is ONLY for use in patients who are already tolerant to opioid therapy

of comparable potency. Use in non-opioid tolerant patients may lead to

fatal respiratory depression. Overestimating the DURAGESIC

dose when converting patients from another opioid medication can result

in fatal overdose with the first dose see DOSAGE and ADMINISTRATION –

Initial DURAGESIC Dose Selection - section of full

Prescribing Information for further information. Due to the mean

elimination half-life of approximately 20-27 hours, patients who are

thought to have had a serious adverse event, including overdose, will

require monitoring and treatment for at least 24 hours.

DURAGESIC can be abused in a manner

similar to other opioid agonists, legal or illicit. This risk should be

considered when administering, prescribing, or dispensing DURAGESIC in situations where the healthcare professional is concerned about increased risk of misuse, abuse, or diversion.

Persons at increased risk for opioid abuse include those with a

personal or family history of substance abuse including drug or

alcohol abuse or addiction or mental illness e.g., major depression.

Patients should be assessed for their clinical risks for opioid abuse

or addiction prior to being prescribed opioids. All patients receiving

opioids should be routinely monitored for signs of misuse, abuse, and

addiction. Patients at increased risk of opioid abuse may still be

appropriately treated with modified-release opioid formulations;

however, these patients will require intensive monitoring for signs of

DURAGESIC patches are intended for transdermal use on intact skin only. Do not use a DURAGESIC patch if the seal is broken or the patch is cut, damaged, or changed in any way.

application site and surrounding area to direct external heat sources,

such as heating pads or electric blankets, heat or tanning lamps,

saunas, hot tubs and heated water beds, while wearing the system. Avoid

taking hot baths or sunbathing. There is a potential for

temperature-dependant increases in fentanyl released from the system

resulting in possible overdose and death. Patients wearing DURAGESIC

systems who develop fever or increased core body temperature due to

strenuous exertion should be monitored for opioid side effects and the

DURAGESIC dose should be adjusted if necessary.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

DURAGESIC - fentanyl patch Ortho-McNeil-Janssen Pharmaceuticals, Inc.-----DURAGESIC Fentanyl Transdermal System CII. Full Prescribing Information.

The onset, duration, and Prepare to apply a DURAGESIC patch: Choose the time of day that is best for you to apply DURAGESIC DURAGESIC- fentanyl patch.

Welcome. What is DURAGESIC®?

Duragesic and Durogesic / ˌ d ɜːr ə ˈ dʒ iː z ɪ k / are trade names of fentanyl transdermal patches, used for relief of moderate to severe pain. The patches.

DURAGESIC is: A strong Do not apply more than 1 patch at the same time unless your healthcare provider tells you to. You should wear the DURAGESIC patch.

The fentanyl skin patch is only used for opioid If you need to apply more than 1 patch at a time, place the patches far enough apart so that the edges do not.